In general, smokers have 15 percent chance of developing lung cancer. This percent is very much greater than the non-smokers, according to Richard Houlston, lead author of the study. He says, “Our results show that some smokers with BRCA2 mutations are at an enormous risk of lung cancer — somewhere in the region of 25 percent over their lifetime.”He said that every year, lung cancer takes more than a million lives. The biggest thing that can be done is to persuade people to stop smoking.The study was conducted by Institute of Cancer Research in the United Kingdom. The study showed the connection between BRCA2 gene defect and lung cancer by analyzing the DNA of 16,000 people without lung cancer and 11,000 with the disease.Connection between squamous cell lung cancer and CHEK2 gene defect was also found by this study published in the journal Nature Genetics.
via Gene Defect may lead to Lung Cancer in 1 in 4 Smokers | Techsonia.